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MDMA

2
episodes
2
thinkers
6h
of conversation
7
books & papers
6
terms defined

The neighbourhood: MDMA and the ideas it travels with. Drag to roam, click a star for the episode, click a neighbour to travel.

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The lexicon

Every term the guests lean on, in plain language. Read one in full, or filter to find it.

    What the corpus says

    The throughline across every conversation that touches this idea.

    MAPS has raised about $110 million over 35 years to integrate psychedelics into therapeutic practices.
    MDMA-assisted therapy shows a 67% PTSD remission rate for the dissociative subtype, outperforming traditional therapies.
    The FDA is expected to approve MDMA for PTSD treatment by the end of 2023, marking a milestone in psychedelic therapy.
    MDMA enhances memory processing by reducing amygdala activity and increasing connectivity with the hippocampus.
    The backlash against psychedelics in the 60s was driven by their potential for social change, not just negative experiences.
    Classic psychedelics like LSD and psilocybin are physiologically safe and non-addictive, acting primarily on the serotonin 2A receptor.
    MDMA is a 'heart trip' psychedelic, contrasting with the 'head trip' of classic psychedelics, with distinct effects on ego and self-perception.
    Psilocybin shows an 80% success rate in smoking cessation studies, outperforming traditional methods significantly.
    Tobacco and alcohol cause far more deaths than all illegal drugs combined, challenging societal drug focus.
    Psychedelics can potentially shift paradigms in science and creativity, as seen in historical breakthroughs like PCR.

    Voices on MDMA

    7 standout quotes from across the corpus.

    Go read

    7 books and papers cited across these episodes.

    For the specialist

    What experts find new

    5 expert-level takeaways for a specialist reader.

    At the frontier

    Still unresolved

    3 open questions flagged across these conversations.

    The thinkers

    Who takes this idea on, by how often they return to it.

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    Adjacent ideas