All topics / genomics
Topic
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Genomics
2
episodes
2
thinkers
5h
of conversation
10
books & papers
5
terms defined
The neighbourhood: genomics and the ideas it travels with. Drag to roam, click a star for the episode, click a neighbour to travel.
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The lexicon
Every term the guests lean on, in plain language. Read one in full, or filter to find it.
What the corpus says
The throughline across every conversation that touches this idea.
The human genome is 99.9% identical across individuals, emphasizing shared humanity despite diversity.
Manolis Kellis · Manolis Kellis: Human Genome and Evolutionary Dynamics
SARS-CoV-2's genome was sequenced within a week of the first sample, accelerating vaccine development.
Manolis Kellis · Manolis Kellis: Human Genome and Evolutionary Dynamics
Evolutionary signatures in genomics reveal 99% of the human genome is non-coding, yet crucial for understanding genetic evolution.
Manolis Kellis · Manolis Kellis: Human Genome and Evolutionary Dynamics
Viruses like SARS-CoV-2 evolve rapidly, with mutations like D614G significantly enhancing human transmission.
Manolis Kellis · Manolis Kellis: Human Genome and Evolutionary Dynamics
Human genetics has surpassed model organisms in research focus due to vast data from human populations.
Manolis Kellis · Manolis Kellis: Human Genome and Evolutionary Dynamics
Dmitry Korkin's team mapped the 3D structure of COVID-19 proteins, advancing understanding of its structural genomics.
Dmitry Korkin · Dmitry Korkin: Computational Biology of Coronavirus
COVID-19's R naught varies between 1.5 and 3, significantly lower than measles' R naught of 15, impacting transmission strategies.
Dmitry Korkin · Dmitry Korkin: Computational Biology of Coronavirus
Nanoparticle vaccines mimic virion particles, potentially reducing infection by competing with actual viruses.
Dmitry Korkin · Dmitry Korkin: Computational Biology of Coronavirus
Agent-based simulations reveal that asymptomatic COVID-19 carriers are highly contagious, especially in the first week.
Dmitry Korkin · Dmitry Korkin: Computational Biology of Coronavirus
Coronaviruses have at least 29 proteins, offering more complexity than the 8-9 proteins in influenza viruses.
Dmitry Korkin · Dmitry Korkin: Computational Biology of Coronavirus
Voices on genomics
5 standout quotes from across the corpus.
Go read
10 books and papers cited across these episodes.
For the specialist
What experts find new
6 expert-level takeaways for a specialist reader.
At the frontier
Still unresolved
3 open questions flagged across these conversations.
The thinkers
Who takes this idea on, by how often they return to it.