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Daphne Koller

computer scientistengineerartificial intelligence researcheruniversity teacher

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machine learning online education CRISPR uncertainty calibration drug discovery disease modeling

Daphne Koller is an Israeli-American computer scientist. She was a professor in the department of computer science at Stanford University and a MacArthur Foundation fellowship recipient. She is one of the founders of Coursera, an online education platform. Her general research area is artificial intelligence and its applications in the biomedical sciences. Koller was featured in a 2004 article by MIT Technology Review titled "10 Emerging Technologies That Will Change Your World" concerning the topic of Bayesian machine learning.

Across 1 conversation, Daphne Koller ranges across machine learning, online education, CRISPR. Machine learning's role in health is expanding due to improved data production technologies, overcoming past limitations of dataset quality. Animal models often fail in translating disease findings to humans, prompting a shift towards 'disease in a dish' models using iPSCs.

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Disease in a dish models using iPSCs have been enabled by technology only available in the last 5 to 10 years, allowing for differentiation into specific cell types with individual genetics.

#93Daphne Koller: Biomedicine and Machine Learning

Polygenic risk scores quantify genetic variations contributing to disease risk, with differences sometimes being factors of 10 or 12 between high and low risk individuals.

#93Daphne Koller: Biomedicine and Machine Learning

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