All topics / CRISPR
Topic
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CRISPR
3
episodes
3
thinkers
7h
of conversation
10
books & papers
7
terms defined
The neighbourhood: CRISPR and the ideas it travels with. Drag to roam, click a star for the episode, click a neighbour to travel.
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The lexicon
Every term the guests lean on, in plain language. Read one in full, or filter to find it.
What the corpus says
The throughline across every conversation that touches this idea.
Chris Mason argues humanity's awareness of extinction gives us a moral duty to preserve life across generations.
Mason believes humanity has the best chance of long-term survival, potentially addressing cosmic challenges like the heat death of the universe.
Mars is considered a viable option for colonization, with its gravity and potential habitats like lava tubes offering protection.
The cost of space travel remains high, with Axiom's mission to the ISS costing approximately $55 million per trip.
CRISPR technology is advancing towards modifying genes for health and survival in space, such as reactivating pseudogenes.
Manolis Kellis argues that understanding human disease requires embracing the complexity of genetic variants beyond protein-coding genes.
Manolis Kellis · Manolis Kellis: Biology of Disease
CRISPR technology revolutionizes genome editing by simplifying the guiding process, not the cutting or fixing.
Manolis Kellis · Manolis Kellis: Biology of Disease
The FTO gene, once misunderstood, is linked to obesity through distant gene regulation involving IRX3 and IRX5.
Manolis Kellis · Manolis Kellis: Biology of Disease
Alzheimer's disease genetics indicate significant roles for microglia, not neurons or astrocytes, in disease progression.
Manolis Kellis · Manolis Kellis: Biology of Disease
Machine learning's role in health is expanding due to improved data production technologies, overcoming past limitations of dataset quality.
Daphne Koller · Daphne Koller: Biomedicine and Machine Learning
Animal models often fail in translating disease findings to humans, prompting a shift towards 'disease in a dish' models using iPSCs.
Daphne Koller · Daphne Koller: Biomedicine and Machine Learning
CRISPR technology enables precise introduction of pathogenic mutations into healthy cells, facilitating comparative studies in disease research.
Daphne Koller · Daphne Koller: Biomedicine and Machine Learning
Voices on CRISPR
12 standout quotes from across the corpus.
Go read
10 books and papers cited across these episodes.
For the specialist
What experts find new
6 expert-level takeaways for a specialist reader.
At the frontier
Still unresolved
5 open questions flagged across these conversations.
The thinkers
Who takes this idea on, by how often they return to it.